Abstract

We wish to report 2 cases of dyskeratosis congenita with pigmentation, dystrophia unguium and leukoplakia oris, a very rare dermatosis, and the response of the lesions of the oral mucosa of 1 of the patients to androgenic medication. REPORT OF CASES1 Case1.—J. W.,2a man aged 25, American, of Jewish parentage, registered at the Skin and Cancer Unit of the New York Post-Graduate Medical School and Hospital on Jan. 28, 1943, presenting cutaneous lesions of fourteen years' duration. He has two brothers and one sister. The parents and the grandparents were not consanguineous. The mother was born in Russia, and the father is American of Polish extraction. The parents stated that as far as they knew none of their near or distant relatives ever had a similar anomaly. The paternal grandmother had frequent epileptic convulsions after she was 8 years of age.

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