Abstract
Eprosartan is an angiotensin II receptor antagonist. Dysgeusia and burning mouth syndrome attributed to angiotensin converting enzyme inhibitors have been reported.1 Several case reports related to angiotensin II receptor antagonists...
Highlights
We found no evidence that surgeons in any of the three categories who performed more than six primary melanoma excisions annually had better outcomes than those who performed fewer excisions
We found no evidence that any type of surgeon performing excisions of primary melanomas regularly had a better outcome than those who carried out fewer excisions, possibly because wide local excision is a relatively simple procedure
Taste disorders related to angiotensin II receptor antagonists had not been described in clinical trials,[2] but several cases of dysgeusia have been reported in patients treated with losartan[3,4,5] and with valsartan.[6]
Summary
We found no evidence that surgeons in any of the three categories who performed more than six primary melanoma excisions annually had better outcomes than those who performed fewer excisions. The data show that the growth in dermatological surgeons excising primary melanomas has had no adverse affect on patient outcome. We found no evidence that any type of surgeon performing excisions of primary melanomas regularly had a better outcome than those who carried out fewer excisions, possibly because wide local excision is a relatively simple procedure.
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