Abstract
Among disturbances of several functions of anterior lobe of pituitary, only two are susceptible to treatment with any assurance of success at present. These are dysfunctions in supply of growth-promoting and gonadotropic factors, which will be discussed in detail. Although thyrotropic extracts of anterior lobe of pituitary have been shown to act in some persons, it has not yet been possible to secure sustained stimulation of thyroid in hypothyroid patients.1Neither is there adequate evidence to warrant routine irradiation of pituitary in an attempt to reduce production of thyrotropic substance in patients with persistent thyrotoxicosis. The factors involved in pituitary stimulation of adrenal glands are still further removed from immediate application in human therapy. The dysfunctions known under such terms as basophilism, Cushing's syndrome or the adrenogenital syndrome will be discussed in another article of this
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More From: JAMA: The Journal of the American Medical Association
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