Abstract
AbstractThis part describes the mechanism of the dysfunction of the immune regulatory system of rhinosinusitis. The immune regulatory system is divided into acquired immune system and innate immune system. They jointly maintain the immune balance of the nasal mucosa, which is an important part of the local mucosal immune system, and plays an important role in defense through the immune active components. CRS is due to the effective barrier function of epithelium, through inflammation, cytokines, T and B lymphocytes, and congenital lymphocytes (ILCs) and other functions, resulting in the disorder of immune regulatory system. At present, it can be treated by immunomodulators, antibiotics, antihistamines and leukotrienes receptor antagonists and saline irrigation.
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