Abstract
A 33-year-old man with a history of sickle cell β-thalassemia (a combination of sickle hemoglobin [HbS] and thalassemia hemoglobin that has a diminished capacity of β-chain synthesis) was referred from the emergency department to the oral medicine clinic at Brigham and Women's Hospital, Boston, for management of acute onset of increasingly severe sharp pain throughout the right mandible. The patient reported having intense sharp shooting pain of the right mandible extending to the right temporomandibular joint, ear and forehead for three days.
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