Abstract
Dysembryoplastic neuroepithelial tumor (DNT) is a mixed neuronal‐glial tumor associated with a history of partial complex seizures. This uncommon lesion must be disting‐uished from other infiltrating gliomas with similar histo‐logical features. DNT frequently affects the temporal and frontal lobes of adolescents and young adults. On neuroimaging, the tumor is well demarcated and located in the superficial layers of the cortex. The presence of intracortical nodules is a positive sign indicating DNT. DNT can be divided into complex and simple forms. Complex forms comprise specific glioneuronal elements, glial nodules and/or cortical dysplasia while the simple forms may be composed of glioneuronal elements only. Glioneuronal elements consist of oligodendroglial‐like cells which often exhibit alveolar and microcystic patterns. In addition, mature neurons of varying size may be present within the mucinous matrix. Surgical resection is usually sufficient for the treatment of DNT. The heterogeneous histology of DNT supports the hypothesis that it is derived from cells in the subpial granular layer.
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