Abstract

Rosacea is a chronic inflammatory disease that primarily affects young and middle-aged Caucasian women. Its etiology is multifactorial and appears to be determined by genetic predisposition, alteration of the neurovascular and immune response, as well as an altered dialogue with the microbiota. Additionally, the disease has been linked to gastrointestinal disorders such as Helicobacter pylori infection or small intestine bacterial overgrowth and even neurological disorders such as Parkinson's disease, revealing the existence of a brain-gut-skin axis.

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