Abstract

The rate at which corneal stroma imbibes water is shown to be related to the flow conductivity and the slope of the imbibition pressure-hydration relationship. The equation that gives imbibition rate in terms of these static (time invariant) properties was obtained previously from a purely physicochemical treatment of water movement in a swelling membrane. A new experimental procedure to obtain imbibition pressure and flow conductivity as a function of hydration is described. The new procedure is more rapid and economical of tissue material needed than are previous methods. Flow conductivity appears to be related only to the physical properties of the stroma whereas imbibition pressure is related to both physical and chemical properties. The rate of water imbibition, therefore, is related to both the physical and chemical properties of the stroma.

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