Abstract
Long-term dynamics of the incidence pulmonary tuberculosis in the Tomsk region was studied. It was shown that in all considered cases the dynamics is the unsteady oscillatory process with complex modulation: there are cyclic trends with the period of 20 and more years and fluctuations of a shorter periods. The relation of the incidence of pulmonary tuberculosis with tubercle bacilli in sputum with the air temperature and precipitation has been revealed. The coincidence is found during the cyclical trends of morbidity (26.4 y.) and precipitation (26.7 y.). The dependence of long-term epidemic process from the weather-climate changes is assumed. We have found a link between the seasonal dynamics of the tuberculosis and air temperature as well as the intensity of solar ultraviolet radiation (UV-B) in Tomsk. The high incidence of tuberculosis (above average annual) is noted from November to April, low - in June-September. The vitamin D role in seasonal variations of incidence is discussed.
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