Abstract
The purpose of the study was to analyse quality of life (QoL) indicators in patients with metabolically healthy obesity (MHO) associated with ≥ 5% weight loss. Material and Methods — The study involved 44 females with MHO (according to the IDF criteria of the metabolic syndrome (MS), 2005) and 33 females with metabolically unhealthy obesity (MUHO) aged 19-59 years. To assess QoL, we used the SF-36 questionnaire (Medical Outcomes Study – Short Form 36). Results — Initially QoL indicators in both groups were not significantly different statistically. The physical component of health (PHsum) in the MHO and MUHO groups averaged 53.9±6.7 & 50.6±6.3 points (p=0.032). The mental component of health (MHsum) averaged 42.1±1.8 & 45.1±1.8 points (p=0.255). The ≥5% decrease in body weight (from the initial body weight) after 6 months led to an increase in the indicators of physical role functioning by 11.6%, vitality by 12.8%, social functioning by 11.2%, emotional role functioning by 11.9%, mental health by 8.8% (p<0.05) in the MHO group, while in the MUHO group the indicators of physical role functioning increased by 24.6%, emotional role functioning by 39.5%, and mental health by 9.2 % (p<0.05). Conclusion — The MHO group is characterized by higher physical component of health, without a statistically significant difference in the indicators of each of the 8 scales of the SF-36 questionnaire. A ≥ 5% decrease in the body mass in patients of both groups is accompanied by the increase in the indicators of QoL.
Highlights
Quality of life (QoL) is the integral assessment of patients’ physical, mental, and social functioning, based on their subjective perception
When assessing quality of life of patients with metabolically healthy obesity, it is necessary to consider the fact that this term refers exclusively to manifestations of cardiovascular pathology, carbohydrate and lipid metabolism disorders [17]
Gynecological pathology was the most wide-spread one, i.e. it was observed in 50% of patients with metabolically healthy obesity (MHO) and in 70% of patients with metabolically unhealthy obesity (MUHO), joint pathology was detected in 6.7% of patients with MUHO and was not detected in patients with MHO
Summary
Quality of life (QoL) is the integral assessment of patients’ physical, mental, and social functioning, based on their subjective perception. It has been determined that obesity has a negative impact on the quality of life indicators; weight loss has a distinct positive effect on these parameters [3,4,5,6,7]. Up until recently, unified definitions of metabolically healthy obesity (MHO) have not been developed, which consistently affects the variability of data regarding its prevalence. After analysing 27 studies using 30 different definitions, the prevalence of this obesity phenotype ranged from 10 to 51% [9]. According to the 2013 BioSHaRE-EU Healthy Obese research project, which included 10 large-scale cohort studies using more stringent MHO criteria – none of the metabolic syndrome (MS) criteria, the MHO [
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