Abstract
Introduction. Currently, COVID-19, which is rapidly spreading around the world in the form of a pandemic, is a serious public health problem that poses a significant epidemiological and medico-social threat to the population and its quality of life, and affects all spheres of public life and economy. Aim. To assess the degree of influence of the pandemic of the new respiratory viral infection COVID-19 on the level of registered primary morbidity by classes of diseases, including the class "Diseases of the respiratory system" in the territory of the Far Eastern Federal District.Materials and methods. To implement the tasks of the study, a complex of analytical, epidemiological and statistical studies was carried out. Methods used: epidemiological analysis and monitoring, statistical, comparative and correlation analysis and methods for analyzing time series. Epidemiological and statistical assessment of the incidence of the population was carried out on the basis of ICD-10 according to the data of the state statistical monitoring of the incidence of the population of the Russian Federation for 2019-2020 using the database of the Ministry of Health of the Russian Federation, the Central Research Institute of Organization and Informatization of Healthcare of the Ministry of Health of the Russian Federation.Results. The pandemic of the new respiratory viral infection COVID-19 significantly changed the dynamics of the registered morbidity in the adult population, which dropped sharply in all ICD-10 classes, most intensively in the classes "Diseases of the endocrine system" (by 27.8%), "Diseases of the blood and hematopoietic organs" (by 22.6%), "Neoplasms" (by 21.1%), "Diseases of the circulatory system" (by 18.5%), with the exception of the class "Diseases of the respiratory system", the level of primary morbidity for which in the territory of the Far Eastern Federal District in 2020 increased by 23.9%. The most common and severe clinical manifestation of COVID-19 is bilateral pneumonia, the incidence of which among the adult population in the Far Eastern Federal District increased 2.7 times, and in the territory of the Russian Federation – 3.8 times. At the same time, the incidence of pneumonia in the child population decreased by 36.4%. Along with the growth of acute forms of respiratory pathology during the COVID-19 pandemic in the Far Eastern Federal District, the level of registered primary morbidity of chronic respiratory diseases decreased: chronic bronchitis (by 22.3%), bronchialasthma (by 20.8%), COPD (by 3, 6%).Conclusion. The negative dynamics of the growth of the registered morbidity of the population can have negative consequences due to the late detection and untimely diagnosis of chronic forms of pathology, including respiratory diseases, their progression and the development of life-threatening complications of the disease and, as a consequence, an increase in mortality from these causes of the population, who did not receive timely and adequate medical assistance.
Highlights
Seroprevalence increased from 38.6% to 54.5% during the analyzed period
Уровень серопревалентности к SARS-CoV-2 среди жителей Хабаровского края на фоне эпидемии COVID-19 // Журнал микробиологии, эпидемиологии и иммунобиологии
Summary
СРАВНИТЕЛЬНАЯ ХАРАКТЕРИСТИКА ОСНОВНЫХ МАРКЕРОВ SARS-COV-2 СРЕДИ УСЛОВНО-ЗДОРОВОГО НАСЕЛЕНИЯ Г. Оценка выявляемости РНК SARS-CoV-2 и уровней серопревалентности среди условноздорового населения г. Наличие РНК вируса определяли методом ПЦР в носоглоточных мазках, антител класса G к спайковому (S) протеину SARS-CoV-2 – в сыворотке крови методом ИФА. Aim. The objective of the research was evaluation of SARS-CoV-2 RNA detection rate as well as seroprevalence levels among conditionally healthy population of Khabarovsk city during different periods of COVID-19 pandemic. Иначе гогих странах зафиксирован рост заболеваемости новой воря, один человек, зараженный SARS-CoV-2, потенкоронавирусной инфекцией, что может свидетельство- циально может заразить до 6 человек, находящихся в вать о риске формирования третьей волны COVID-19. Серологические и молекулярно-генетические исследования, включающие качественную оценку наличия РНК вируса в носоглоточных мазках и специфических антител в сыворотке крови, стали основой, как для контроля эпидемической обстановки, так и для планирования неспецифических и специфических мероприятий по профилактике COVID-19 [3]. Что оперативный мониторинг за показателями, влияющими на динамику эпидемического про-
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