DYNAMICS OF INDICATORS IN PLATELET HEMOSTASIS IN POLYTRAUMA AND ENLARGED BODY MASS INDEX.

Abstract

The aim: Analyze the dynamics of indicators in platelet hemostasis in polytrauma and enlarged body mass index. Materials and methods: A comprehensive study of hemostasis was performed in 224 sick with polytrauma and high body mass index within a month and on the 360th day. Results: In Group I, the aggregation time was shortened during stimulation of ristomycin by 25% from day 1 to day 3. In patients in the II group, with the addition of ADP, the presence of hyperaggregation of platelets was determined from the 1st to the 3rd day and from the 30th to the 360th (a 36% reduction in time compared to the control was determined). In patients in the III group, ADP-aggregation was reduced on the 1st day (by 34%), after which hypoaggregation was noted (from the 3rd to the 14th and on the 360th day) with an increase in the rate of approximately 33% compared to the control group, after which there was a persistent hyperaggregation from 30 to 360 day with a 25% reduction in aggregation time. Conclusions: An individual response of platelets to damage was established depending on the severity of polytrauma and increased body mass index.