Abstract
The article reflects the results of researches conducted on studying the changes in the morphoimmunological indicators of the mammary gland secretion in cows with subclinical mastitis in the dynamics of its development. Thus, in the initial stages of the subclinical mastitis in cows and its further development, significant changes occur in the immune status and homeostasis of sick animals, characterized by the occurrence of a strong inflammatory reaction in the mammary gland against the background of a weakening of the general nonspecific resistance in the udder of sick animals. Already on the third day of the disease, the amount of milk lysozyme was 0.974, total immunoglobulins – 2.99 g/L, circulating immune complexes – 0.163, the number of somatic cells increased by 25.7% and amounted to 2.3 ths/ml, neutrophils – 77.2%, in comparison with the first day of the disease, which indicates the activation of the protective function of the mammary gland. Thus, with the further subclinical mastitis development, significant changes occur in the immune status and homeostasis of sick animals, characterized by the occurrence of a strong inflammatory reaction in the mammary gland against the background of a weakening of the general nonspecific resistance in the udder of sick animals.
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