Dynamically observing the value of the changes of serum sex hormone levels of early pregnancy after drug-induced abortion

Abstract

Objective To observe the value of the changes of serum β-human chorionic gonadotropin(β-HCG),estradiol(E),progesterone(P)Levels of early pregnancy after drug-induced abortion dynamically.Methods Assessing 55 women proved pregnant by urine or blood HCG retrospecticly,who had terminated their pregnancy by mifepristonr and misoprostol.Meanwhile the serum levels of β-HCG,E,P were monitored dynamically.Results Among the 55 patients,the levels of β-HCG,E and P had significant decreased(t_(β-HCG)=4.845,t_E=7.655,t_P=11.390,P＜0.01).On the 7th day,the levels of E and P decreased to the level of follicle phase.The level of E on the 14th day was higher than that of 7th day(t_E=9.089,P＜0.05); the level of P was higher than that of 14th day(t_P=2.910,P＜0.05).Conclusion Detecting the serum hormone' s levels after drug-induced abortion by chemiluminescent immunoassay,we can assess indirectly the value of administration of mifepristone and misoprostol,predict the prolonged vaginal bleeding after drug-induced abortion,and the outcome of the treatment,which determine wether need another curestage. Key words: Abortion,induced; Chorionic gonadotropin,beta suhunit,human; Estradiol; Progesterone