Abstract
A two-strain rotavirus model with vaccination and homotypic protection is proposed to study the survival of the two strains of rotavirus within the host. Corresponding to the different efficacy of monovalent vaccine against different strains, the vaccination reproduction numbers of the two strains and the reproduction numbers of their mutual invasion are found. Based on the existence and local stability of equilibria, our results suggest that the obtained reproduction numbers determine together the dynamics of the model, and that the two-strain rotavirus dies out as both the numbers is less than unity. The coexistence of two strains, one of which is dominant, is also related to the two reproduction numbers.
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