Abstract
In this paper, fiber Bragg grating (FBG) is used as a fully distributed sensor to monitor tissue dynamic temperature changes during laser-induced interstitial thermotherapy (LITT). This work is mainly realized by the correlative single particle (CSP) algorithm, which is a rapid algorithm for spectrum reconstruction. Experimental LITT treatment was set up by using 532nm laser applicator on a piece of fresh liver tissue. In the experiments, the dynamic temperature profile was successfully demodulated with a refreshing speed of 11 seconds. With the aid of dynamic feedback, the thermotherapy boundary temperature was well controlled around 35°C during the treatment by adjusting the laser output power in real-time. Therefore, with this method, it is promising to precisely control the tissue temperature in vivo and improve the safety of the LITT remarkably.
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