Abstract

The dynamic surface properties of mixed solutions of a cationic surfactant - cetyltrimethylammonium bromide (CTAB) - and different types of deoxyribonucleic acid in both linear (ctDNA) and plasmid (pDNA) forms were studied by surface tensiometry and dilational surface rheology. The dynamic surface elasticity and the dynamic surface tension depended strongly on the DNA type. The adsorption layers of ctDNA/CTAB solutions exhibited strong elastic behavior in a wide range of surfactant concentrations. Contrariwise, the addition of plasmid DNA altered the dynamic surface elasticity of CTAB solutions only slightly. The significant difference in the size of macromolecules, their conformation, and, thereby, their effective charge leads to the formation of DNA/CTAB complexes of different surface activity and causes drastic changes in the rheology of the adsorption layer.

Full Text
Paper version not known

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call

Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.