Dynamic Observation of Vascular Regeneration in Femoral Head Necrosis: a 5-Year Follow-Up Case Report

Abstract

Femoral Head Necrosis (FHN) is an invasive hip disease of skeletal system, which associated with vascular dysfunction. Therefore, vessels regeneration and follow the posterolateral direction are regarded as a potential therapy target for FHN. We report a case of FHN that was treated by successful regeneration of the internal circumflex femoral artery via targeted Lipoaspirate (LPS) infusion and biomechanical support. A 35-year-old man with FHN involved. LPS isolated from the abdominal subcutaneous fat and infuse into the internal circumflex artery approximately seven times at every 1.5 months in both femoral heads. Besides, the porous tantalum rod was grafted after the first LPS infusion on each side. After the 5-year follow-up study, the primary outcomes showed obvious improvement in the number, distribution, and diameter of blood vessels in the ischemic area. In addition, the patient was now able to perform the daily activities; the congestive area increased from 73.4% to 94.2% on the left side and from 0% to 71.8% on the right side. The Harris Hip Score improved from 22 to 91. Multiple LPS infusions via the internal circumflex femoral artery combined with porous tantalum rod grafting offers an alternative treatment option for FHN.