Abstract

Capsular polysaccharide (SPS) is an integral component of gram negative bacteria, Klebsiella . The interaction of SPS isolated from Klebsiella K40 serotype with oppositely charged pure surfactants and cationic-nonionic mixed surfactants were investigated by dynamic light scattering and viscometric technique. Variation in the hydrodynamic radius and zeta potential were studied by dynamic light scattering method. Nature of the interaction is governed by concentration of the surfactants, charge density, surfactant head group and the CMC of the surfactants. Micellar effects of the pure and mixed surfactants on binding with the SPS are presented in this paper.

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