Abstract
AbstractOxidative stress is intimately linked to cellular energy balance and occurs when there is an imbalance between production and accumulation of reactive oxygen species in cells and tissues and the ability of a biological system to keep in a redox steady state. While protein carbonyls are an easily detectable marker of oxygen metabolism and oxidative stress, all methods to date have required significant sample preparation and do not provide the ability to measure dynamic changes. To overcome this problem, we develop the first method for measuring in vivo concentration changes of protein carbonyls using a minimally invasive optical fibre biosensor. We use this biosensor to measure redox balance and oxidative stress within living systems by measuring dynamic in vivo concentration changes of protein carbonyls.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
