Abstract

PURPOSE: Dynamic hyperinflation (DH) causes exercise limitation and exertional dyspnea in patients with COPD. Exertional desaturation (ED) also occurs commonly in COPD and multiple mechanisms have been postulated to cause ED. However, neither routine pulmonary function testing nor imaging predicts ED accurately. In this study, we evaluated the relationship between DH and ED during six-minute walk testing (6MWT).

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