Abstract
Racemic narwedine may be resolved by means of a dynamic diastereomeric salt formation using di- p-toluoyl- d-tartaric acid. Both the 1:1 and 2:1 salts are formed in excellent yields and diastereomeric excesses. These salts are reduced in a highly diastereoselective and chemoselective manner to give (−)-galanthamine.
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