Abstract
AIM: To investigate the characteristics of pathological changes in the gastric mucosa after anti-Helicobacter pylori (H pylori ) therapy. METHODS: The samples were obtained through electronic gastroscope or operation and divided into two groups: therapy group (n =32) in which the patients received standard anti-H pylori therapy; and control group (n =25) without anti-H pylori therapy. Histological examinations were carried out after gastroscopic inspection or operation, half a year and one year later. RESULTS: H pylori in the mucous membrane of the stomach in all 32 cases in therapy group diminished or disappeared and pathological changes (inflammation, intestinal metaplasia and dysplasia) attenuated to some extent. There were significant differences between samples at different time points of examination (P 0.05). There was significant difference between samples of therapy and control groups (P <0.05).
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