Abstract
Background. Central vein catheterization (CVC) is a major risk factor for central vein stenosis (CVS). Repetitive contacts of the CVC to the blood vessel wall results in inflammation, microthrombi, hyperplasia of the intima, fibrosis and thus development of CVS. This article reports the correlation of duration and frequency of CVC in patients with CVS. Method. A matched case control study was conducted in Cipto Mangunkusumo Hospital. Samples were gathered from the medical record. Multivariate statistical comparisons were done using Chi-square tests. Results. Fifty four out of 717 patients underwent CVC for HD had CVS. 32 patients with CVS included in the study with 128 non-CVS patients included as control. Duration of CVC >6 weeks does not increase the risk of CVS (p= 0.207), whilst the odds ratio of CVS on the frequency of CVC >2 times is 30 times compared to those underwent 2 times increased the risk of CVS. Longer duration of CVC for HD did not increase CVS rate. Keywords: Catheter, central vein, hemodialysis, stenosis
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