Duplex ultrasonographic assessment of gut blood flow velocity: effect of meal composition in normal full-term newborns after first feed.

Abstract

We used transcutaneous duplex Doppler ultrasound to measure superior mesenteric artery and celiac artery blood flow velocity in 45 normal healthy newborn infants. Doppler indices of PSV, TAMV, EDV, and PI were measured immediately before and after feeding at 15 minute intervals up to 75 minutes. Maximal changes were compared with preprandial baseline values. There were no significant differences between the preprandial and postprandial blood pressures and heart rates. In the superior mesenteric artery the PSV, TAMV, and EDV rose progressively and peaked 30 minutes after feeding in both the milk-fed group and the 5% glucose, water-fed group over baseline (73 versus 41% and 110 versus 63%, 130 versus 100%) (P < 0.05). The PI decreased significantly in the milk-fed group only. There were no significant changes in any blood flow velocity parameters derived from the celiac artery. We conclude that duplex ultrasonography provides a noninvasive means of studying the reactivity of the splanchnic arterial circulation to different stimuli. The chemical composition of the meal is a significant factor determining postprandial mesenteric hyperemia.