Abstract
Renal cell carcinoma (RCC) metastasis to duodenum is very rare and only a few case reports are available in the literature. We here reported a patient with solitary duodenal metastasis presented with melena six years after right nephrectomy. The patient underwent upper gastrointestinal endoscopy showing ulcerative mass at the second portion of duodenum and biopsy of this mass was consistent with metastatic RCC. Metastasis work up did not find any other site of malignancy, thus Whipple's operation (Pancreaticoduodenectomy) was performed. In conclusion metastasis from RCC should be considered in mind in patients with history of nephrectomy presenting with gastrointestinal symptoms and a complete evaluation, especially endoscopic examination followed by biopsy, is suggested.
Highlights
Renal cell carcinoma (RCC) has trend to metastasize many years following surgery
We reported a patient with solitary duodenal metastasis presented with gastrointestinal bleeding and melena six years after right nephrectomy
A 59-year-old male was presented with black tarry stools and melena. His medical history showed right radical nephrectomy (6 years ago) with the diagnosis of clear renal cell carcinoma treated with adjuvant immunotherapy
Summary
Renal cell carcinoma (RCC) has trend to metastasize many years following surgery. Metastatic sites for RCC include lungs, bones, liver, adrenal glands and brain; in rare cases, gastrointestinal system can be involved [1].It can involve any section of the bowel and accounts for 7.1% of all metastatic tumors to the small intestine [2]. Renal cell carcinoma (RCC) has trend to metastasize many years following surgery. Metastatic sites for RCC include lungs, bones, liver, adrenal glands and brain; in rare cases, gastrointestinal system can be involved [1].
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