Duodenal lipomatosis

Abstract

A 54-year-old man with a history of tonsillar cancer had a follow-up CT scan, which showed incidental duodenal lipomatosis (A). Two years later, upper endoscopy was performed to evaluate acid reflux. A small hiatus hernia was observed. Starting at the distal end of the bulb and leading to the third part of the duodenum were 10 submucosal lesions 0.5 to 2.0 cm in diameter (B). Probing with the forceps resulted in a shallow pillow sign, and biopsies of three nodules resulted in exposure of underlying fat (C). Pathologic examination revealed typical findings of a submucosal lipoma.