Abstract

Heterotopic duodenal tissue in the Gall Bladder is an extremely rare incidental post mortem finding with unknown clinical significance. Gastric and pancreatic heterotopia is the most common heterotopic tissue found in the gastrointestinal tract. Gall bladder is rarely involved with unknown prevalence rate. It may be associated with cholecystitis or cholecystolithiasis. Etiology of heterotopia is still unknown. We report an autopsy case of a 36-year-old-man with an incidental duodenal heterotopia in gall bladder. Keywords: Duodenum, heterotopia, gall bladder, autopsy

Highlights

  • In Pathology, term heterotopia is defined as the presence of the normal tissue in an abnormal location, without any neural, vascular, or anatomic connection with the main organ

  • CASE HISTORY A 36-year-old-man reported to emergency with complaints of fever, shortness of breath for a few days. He was being treated for extensive bilateral pneumonitis, he died on second day of admission due to respiratory complications

  • Most frequent reported heterotopia are pancreatic heterotopia seen in stomach or gastric mucosa while gastric and pancreatic heterotopia seen in duodenum and jejunum

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Summary

Introduction

In Pathology, term heterotopia is defined as the presence of the normal tissue in an abnormal location, without any neural, vascular, or anatomic connection with the main organ. 1,2 Gastric heterotopia refers to presence of normal gastric mucosal tissue at a non-physiologic site, separate from the surrounding mucosa and entirely separate from stomach. It is a commonly reported epithelial heterotopia, known as heteroplasia (congenital) during organogenesis or metaplasia (acquired) during the process of epithelial repair. CASE HISTORY A 36-year-old-man reported to emergency with complaints of fever, shortness of breath for a few days While, he was being treated for extensive bilateral pneumonitis, he died on second day of admission due to respiratory complications. Lung showed firm, grey red areas while gross examination of gall bladder revealed unremarkable outer surface.

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