Dummy molecularly imprinted polymer (DMIP) as a sorbent for bisphenol S and bisphenol F extraction from food samples

Abstract

Dummy molecularly imprinted polymer (DMIP) was prepared towards bisphenol S and bisphenol F employing bisphenol A as a dummy template. Liquid chromatography with UV and fluorescence detection (LC-UV/FLD) was used for the separation and quantification of these analytes. The maximum adsorption capacity of DMIP was 20.9 mg g−1 and 18.6 mg g−1 for BPS and BPF, respectively. By applying solid phase extraction with DMIP prior to LC-UV/FLD, the limits of detections achieved in food samples can be lowered to 0.5 ng g−1 for BPF and 5 ng g−1 for BPS. Only 5 mg of DMIP sorbent was sufficient to achieve good recoveries (71–113%) and precision (RSD 0.1–3.2%, n = 3) for analyzed liquid food samples spiked at two concentration levels 0.25 mg L − 1 and 0.40 mg L − 1. For preconcentrated pineapple extract spiked with 0.5 mg•L − 1 of both analytes, also very good recovery was obtained (89% for BPS and 99% for BPF), significantly higher than for conventional SPE cartridges such as Oasis HLB and Affinimip®. The analytical characterization of the proposed method makes it suitable for monitoring programs, intended for the assessment of human exposure to bisphenol S in food samples, without using much expensive mass spectrometry detection.