Abstract
Objective: We aimed to evaluate ductus venosus Doppler waveforms before and after amniocentesis in order to investigate any effect of amniocentesis on fetal myocardial hemodynamics. We also evaluated the umbilical artery, uterine artery and fetal mid-cerebral artery Doppler waveforms in order to investigate any relationship with ductus venosus Doppler changes. Methods: The study population consisted of 56 singleton pregnancies having genetic amniocentesis. Twenty seven of them had transplacental needle insertion; whereas 29 of them had non-transplacental amniocentesis. Uterine artery, umbilical artery, mid-cerebral artery and ductus venosus pulsatiliy index and resistance index were measured just before and after amniocentesis. Results: Amniocentesis does not cause any significant changes in fetal ductus venosus Doppler waveforms. There is also no significant changes in uterine artery, umbilical artery, mid-cerebral artery pulsatility and resistance index. Conclusion: Amniocentesis-whether transplacental or not- does not cause any significant effect on fetal myocardial hemodynamics.
Highlights
Genetic amniocentesis (AC) is widely used in obstetric practice
We aimed to evaluate ductus venosus Doppler waveforms before and after amniocentesis in order to investigate any effect of AC on fetal myocardial hemodynamics
The study was conducted prospectively to evaluate the influence of transplacental needle passage on uterine artery (UtA) pulsatility index (PI), resistance index (RI); umbilical artery (UA) PI and RI; ductus venosus (DV) PI and RI; fetal mid-cerebral artery (MCA) PI and RI
Summary
Genetic amniocentesis (AC) is widely used in obstetric practice. Fetal loss rate does not exceed 0.3% to 1.0%.1-3 Second trimester AS is safe, which. There are a few studies regarding the Doppler velocity waveforms after second trimester AC in order to investigate uteroplacental and fetal circulation.[6,7,8] Ductus venosus is the most accurate tool to interprete both fetal cardiac function and Ductus venosus Doppler waveforms before & after amniocentesis myocardial hemodynamics.[8] To the best of our knowledge, this study is the first by investigating ductus venosus Doppler velocity forms after AC. Ductus venosus directs well-oxygenated blood from the maternal circulation to the right atrium in order to supply mainly the fetal heart and the fetal brain.[9]. We aimed to evaluate ductus venosus Doppler waveforms before and after amniocentesis in order to investigate any effect of AC on fetal myocardial hemodynamics
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