Ductal Carcinoma in Situ of the Breast

Abstract

An adult female underwent a breast-wide local excision for ductal carcinoma in situ. Which of the following statement is false regarding ductal carcinoma in situ (DCIS; intraductal) carcinoma of the breast?a.It may present as an incidental lesion on biopsies performed for other reasons.b.It may be associated with calcifications and appear as linear casts or granular on imaging.c.It is always associated with invasive breast cancer.d.Before widespread imaging mammography, it often was identified as a palpable mass. Answer: c. It is always associated with invasive breast cancer. Ductal carcinoma in situ is not always associated with invasive ductal carcinoma, but they can occur together. Certain subtypes of invasive breast cancer, such as triple negative/basal-like breast cancers, are less often associated with DCIS than are the other subtypes.1Doebar S.C. van den Broek E.C. Koppert L.B. et al.Extent of ductal carcinoma in situ according to breast cancer subtypes: a population-based cohort study.Breast Cancer Res Treat. 2016; 158: 179-187Crossref PubMed Scopus (37) Google Scholar Ductal carcinoma in situ may present as an incidental lesion on biopsies performed for other reasons. Ductal carcinoma in situ may be associated with calcifications and appear as linear casts or granular on imaging. Before widespread imaging mammography, DCIS was often identified as a palpable mass.