Abstract
BackgroundFibroadenoma is the most common benign tumor; although malignant, changes are rare. Any changes or increase in size should be evaluated thoroughly to exclude any malignant formation.Case presentationA 25-year-old female presenting to our department complaining of enlargement of the previously stable mass underwent imaging assessment and biopsy which revealed ductal carcinoma in situ changes developed in a fibroadenoma.ConclusionAlthough malignant changes in a fibroadenoma are rare, biopsy of increasing size fibroadenoma is advised to avoid missing any malignant changes; the incidence is more in the complex fibroadenoma.
Highlights
Fibroadenoma is the most common benign tumor; malignant, changes are rare
We diagnosed a case of ductal carcinoma in situ which developed within fibroadenoma that showed a recent increase in size after a long time of stability that warrants biopsy which revealed malignant changes; the patient was seen by breast surgeon that decided to do a lumpectomy
Case Presentation A 25-year-old female is frequently coming to our department to follow up multiple bilateral breast masses by ultrasound; these masses are stable throughout a period of 4 years and appeared
Summary
Fibroadenoma is the most common benign breast neoplasm seen in young women. It is benign, there is a very rare risk to develop malignancy; this risk is more evident in complex fibroadenomas and those with a family history of breast cancer. We diagnosed a case of ductal carcinoma in situ which developed within fibroadenoma that showed a recent increase in size after a long time of stability that warrants biopsy which revealed malignant changes; the patient was seen by breast surgeon that decided to do a lumpectomy. The patient was seen by a breast surgeon that asked for a biopsy of the other masses that was done and revealed benign lesions. The mammogram was very dense (Fig. 4); scattered foci of microcalcification are noted, and the mass could not be identified. In post-contrast breast MRI, the concerned mass exhibited low signal intensity on T2WI (Fig. 5) and demonstrated a rapid enhancement in early post-contrast series (Fig. 6) with washout of the peripheral part of the lesion
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