Abstract
e11503 Background: The main goal in treating DCIS remains the prevention of ipsilateral recurrence and contralateral tumors. Known risk factors for recurrence include multifocal disease, tumor size, nuclear grade, presence of comedo necrosis, hormone receptor (HR) and HER-2 status and young age. Despite the similar distribution of molecular characteristics and treatments among ethnic groups, previous research reported that African Americans (AA) have worse outcomes. Methods: We identified 446 patients with DCIS (395) or microinvasive carcinoma (51), treated between 2008 and 2013, in the Thomas Jefferson University Tumor Registry. Associations between recurrence and demographic factors, histology, and treatment were assessed. Student’s t-test was used to compare age between recurrent and non-recurrent patients, Pearson’s Chi-squared test to test associations between recurrence variables with more than two categories, and Fisher’s Exact test for testing associations between recurrence and two-level categori...
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