Duas formas de apresentação da amiloidose em ORL

Abstract

Objective: To report two cases of amyloidosis with clinical presentation in Otolaryngology, as well as a theoretical review about its pathology, including clinical presentation, diagnosis and therapeutic options. Methods: A retrospective study was made with two cases of amyloidosis diagnosed in our department between 2003 and 2010. We present a case of primary systemic amyloidosis associated with Multiple Myeloma, with presentation in Otolaryngology, and a second case of localized amyloidosis in the larynx. Results: Amyloidosis, either in its localized or systemic form, is relatively rare in Otolaryngology. However, macroglossia is a common symptom of systemic amyloidosis, occurring in up to 20% of patients. The localized amyloidosis primarily affects the larynx, thus being of great importance to the otolaryngologist. Conclusions: Amyloidosis should be part of the differential diagnosis in head and neck lesions, with mandatory exclusion of its systemic form.