Abstract
Application of quantitative myocardial CT perfusion (CTP) for the assessment of coronary artery disease may have a significant effect on patient care as the functional significance of a coronary stenosis can be evaluated through absolute measurement of the downstream myocardial perfusion (MP) both at rest and under exercise or pharmacologic stress. A main challenge of myocardial CTP is beam hardening (BH), arising from the polychromatic nature of x-rays used in CT scanning and the presence of highly attenuating contrast agent in the heart chambers during the CT acquisition. The BH effect induces significant nonuniform shifts in CT numbers which, if uncorrected, can lead to inaccurate assessment of MP. With the recent developments of dual-energy CT (DECT) scanning on clinical scanners, the BH effect on MP measurement could be reduced with the generation of monochromatic images relatively free of BH artifacts from the acquired dual-energy data. Here, we review the different techniques of acquiring dual-energy scans and generating monochromatic images, followed by discussion on the progress of developing a DECT technique with reduced radiation dose for quantitative myocardial CTP.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
