Abstract

Uterine endometrium has extraordinary uniqueness to regenerate after menstrual bleeding, postpartum or after any break in uterine layer integrity throughout women’s lives. Direct cell-cell contacts ensured by tight and adherens junctions, play an important role in endometrial integrity. Any changes in them can alter endometrial permeability and have an impact on the regeneration of uterine layers. Inflammatory environment caused by infections and immune disorders are known to affect mucosal regeneration.

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