Dual macrocyclic chemical input based highly protective molecular keypad lock using fluorescence in solution phase: A new type approach

Abstract

Generally, the non-bonding interactions provide the stability to the host-guest complexes without affecting the molecular identity of macrocyclic host and guest (probe) molecules. As a result, macrocyclic-based systems are far more deserving candidates over the ionic systems, as the chance of chemical bleaching is suitably dodged due to the weaker non-bonding interaction. The present article intends to highlight an unconventional and completely innovative designing strategy to validate the operation of a highly protective opto-chemical keypad lock driven by the macrocyclics. Herein, we have utilized the reversible photoswitching phenomenon between two prototropic forms (cationic and neutral) of Harmine (HM) regulated by the dual macrocyclic components, CTAB and β-CD. Most interestingly, methodology provides the choice of the selection of emission detector one at a time between two available emission channels (416 and 365 nm), which have been considered as the “optical inputs”. Substantial emission intensities of the probe at the respective emission channels have been treated as the “optical outputs”. On the basis of a cautious literature survey, we anticipate that, this kind of designing for a highly protective opto-chemical security device driven by the macrocyclic “chemical inputs” has never explored yet.