Dual-energy computed tomography: a valid tool in the assessment of gout?

Abstract

Gout is the most common inflammatory arthropathy worldwide and the most prevalent inflammatory arthropathy in males. One of the risk factors implicated in the rising prevalence of gout is metabolic syndrome. Gout itself is an independent risk factor for cardiovascular morbidity and mortality. Current imaging modalities for gout lack specificity and sensitivity, especially with atypical presentations. Dual-energy computed tomography (DECT) is a promising new tool for imaging monosodium urate deposits with a high degree of specificity and sensitivity. DECT has the ability to detect subclinical gout, potentially allowing early detection of urate tophi in asymptomatic hyperuricemic patients. DECT could potentially serve as a primary imaging modality in the diagnosis of gout and monitoring response to urate-lowering therapy.