Abstract
Objective. To summarise the results of the past 8 years obtained at the South African Doping Control Laboratory and to compare the results with international statistics. Method. Screening procedures were performed on 14 017 urine samples collected from competitors in 54 different sporting codes during the period 1995 - 2002. Samples were analysed using gas chromatography and gas chromatography/mass spectrometry for the presence of prohibited substances, which are listed by the International Olympic Committee (IOC). Results. The results obtained were compared with those of the IOC-accredited laboratories. Prohibited substances were detected in 300 samples (2.14%), of which 45.6% contained anabolic agents and 34.6% stimulants. The positive samples from the IOC laboratories contained 58.7% anabolic agents and 20.8% stimulants. Testosterone and nandrolone were the anabolic agents most frequently detected in positive samples, both in South Africa and internationally. The ephedrines as a group accounted for most stimulants detected in positive samples. Conclusion. It is of concern that the percentage of positive samples (2.14%) obtained in our laboratory is higher than the 1.70% in IOC laboratories. It is therefore necessary that doping control to curb the use of prohibited substances should continue and expand. South African Journal of Sports Medicine Vol.16(1) 2004: 29-32
Highlights
IntroductionIn 1982 the Department of Pharmacology at the University of the Free State was approached by several sports administrators to analyse urine samples from competitors for the presence of prohibited substances
After thorough testing and inspection by the International Olympic Committee (IOC) (SubCommission Doping and Biochemistry in Sport), accreditation was granted to the South African Doping Control Laboratory (Department of Pharmacology, University of the Free State) in 1995
Narcotic analgesics — hydrolysis of urine followed by alkaline extraction, derivatisation and gas chromatography with a mass selective detector (GC/MSD)
Summary
In 1982 the Department of Pharmacology at the University of the Free State was approached by several sports administrators to analyse urine samples from competitors for the presence of prohibited substances. Analytical procedures were set up for the detection of all chemical substances banned in sport according to the official list of the International Olympic Committee (IOC),[2] which is revised and published annually. After thorough testing and inspection by the IOC (SubCommission Doping and Biochemistry in Sport), accreditation was granted to the South African Doping Control Laboratory (Department of Pharmacology, University of the Free State) in 1995. The aim of this study was to summarise the results of the past 8 years of dope testing at the South African Laboratory (from the time IOC accreditation was awarded), and to compare these results with a summary of statistics from the IOCaccredited laboratories
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