Abstract
Following brief comments on the human factors aspect of traffic accidents and legislation for prohibiting drinking and driving, this article discusses the problem of drugs and driving. Two areas are covered: the metabolism of alcohol and drugs and the effects of drugs on behavior. The latter topic is discussed at length, considering prescription drugs, drug-alcohol interactions, leisure drugs and drugs of abuse, and cannabis. In conclusion it is stated that the technology of detecting and quantitating drugs in biological fluids and methods for assessing their physiological, pharmacological and psychological effects are now sufficiently advanced to warrant the setting up of an expert panel to make recommendations as to future research, legislation and means of disseminating knowledge relevant to the relationship of drugs to road traffic safety similar to that done for alcohol.
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