Abstract
Introduction: Assessment of drug utilisation pattern (DUP) based on World Health Organisation (WHO) drug prescribing indicators would enhance the standards of patient care at all levels of the healthcare. It helps to improve the quality of life in developing countries like Nepal.
 Objective: To assess DUP in patients admitted in ear, nose and throat inpatient department at a tertiary hospital in Eastern Nepal using the WHO prescribing indicators.
 Methods: A hospital based cross-sectional descriptive study was carried out in 96 patients in ENT department of a tertiary care teaching hospital from February-April 2019. Pre-designed proforma was used to collect the relevant data from the medical case sheets and drug charts. Descriptive statistics were calculated using Microsoft Excel 2010.
 Results: Out of 96 patients, 52 (54.17%) were female. Most of the patients (46, 47.18%) were preÂscribed four drugs. Combination of Ibuprofen and Paracetamol (77, 19.74%) was the commonest prescribed drug. Ceftriaxone (62, 63.92%) was the most frequently prescribed systemic antibiotic. The average number of drugs per prescription was 4.06. None of the drugs were prescribed by generic name. Out of 360 drugs, only 118 (30.26%) were prescribed from National List of Essential Medicines (NLEM) and 117 (30.00%) drugs were fixed drug combinations. Ninety two (95.83%) patients had been prescribed at least one antibiotic.
 Conclusions: The prescribing practices of essential medicines, generic drugs, antibiotics and injectÂable drugs showed deviation from the standard recommended by the WHO. The prescribers should be motivated to enhance prescription of drugs by generic names and from NLEM.
Highlights
Assessment of drug utilisation pattern (DUP) based on World Health Organisation (WHO) drug prescribing indicators would enhance the standards of patient care at all levels of the healthcare
The prescribing practices of essential medicines, generic drugs, antibiotics and injectable drugs showed deviation from the standard recommended by the WHO
The findings indicated that prescribers should adhere to the guidelines to prescribe antibiotics appropriately and rationally to the patients
Summary
Assessment of drug utilisation pattern (DUP) based on World Health Organisation (WHO) drug prescribing indicators would enhance the standards of patient care at all levels of the healthcare It helps to improve the quality of life in developing countries like Nepal. According to the WHO, more than 50% of all medicines are prescribed, dispensed or sold inappropriately.[1] The problem is exacerbated in the developing countries like Nepal due to the limited resources and inadequate drug and hospital policy.[2] Drug utilisation research (DUR) is the marketing, distribution, prescription and use of drugs in a society, with special emphasis on the resulting medical, social, and economic consequences It helps to determine the rationale drug therapy and provides evidence based guidance for making various policies at hospital setting.[3] It forms the basis for making amendments in the drug dispensing policies at local and national levels and it holds a crucial place in clinical practice.[4] There have been various. Health Renaissance. 2017; 13(2):50-65. [ Full Text | DOI]
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