Abstract
Prohibition makes some drug use and drug selling a crime by statute, but licit drugs like alcohol are also associated with criminality in myriad ways. Within a prohibition regime, it is difficult but important to distinguish a drug's intrinsic psychopharmacological harms from the harms created or exacerbated by prohibition and its enforcement. Rather than debating the merits of legalization (see MacCoun & Reuter, 2001), we evaluate current epidemiological patterns and mainstream policy instruments within the US prohibition regime, but we go beyond the standard criterion of prevalence reduction by considering harm reduction and quantity reduction as well. We close by speculating about some emerging challenges, including the thizzle scene and the future of performance enhancing drugs.
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