Abstract
Chronic migraine (CM) is a disabling illness that has substantial impact on the patient’s ability to perform routine daily activities and on productivity in the workplace [1, 2]. Management of chronic migraine requires identifying and managing risk factors, establishing limits on the use acute pain and migraine medications to minimize the effects of overuse, initiating non-pharmacologic treatment, and treating neuropsychiatric disorders (e.g., depression, anxiety) and other comorbid conditions (e.g., obesity) that may contribute to increased attack frequency. All these therapeutic recommendations are based on clinical experiences and not on the results of randomized, placebo controlled trials. The primary goals of preventive therapy in subjects with chronic migraine are to reduce the frequency and severity of attacks, to reduce reliance on acute medications, and to improve quality of life.
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