Drug Therapy Problems & Contributing Factors Among Patients with Cardiovascular Diseases in Felege Hiwot Referral and Jimma University Specialized Hospital, Ethiopia

Abstract

Drug therapy problem is a new concept developed around 1990s. It results in increased morbidity and mortality. It is also a common scenario in chronic non communicable diseases, like cardiovascular diseases. Although pharmacotherapy in cardiovascular diseases can improve patient outcome, its benefit can be compromised by drug-related problems. The objective of the research is to characterize the prevalence of drug therapy problems and contributing factors among hospitalized patients with cardiovascular diseases in Felege Hiwot Referral and Jimma University Specialized hospital. Hospital based general cohort study design was used. All admitted patients with cardiovascular disease/s, in Felege Hiwot Referral and Jimma University specialized hospital were included. Most of the data were collected from patient card. Pharmacists in collaboration with a nurse were involved in collecting the data. The data were analyzed using SPSS version 20.0 Descriptive, logistic and linear regressions were used. P value of less than 0.05 was considered statistically significant to study association between risk factors and drug therapy problems. The most common cardiovascular disease encountered were hypertensive heart disease (27, 27.83%), rheumatic heart disease (24, 24.74%) and, functional heart failure and cor pulmonalae (24, 24.74%). A total of 164 number of DTPs were identified with the mean number of DTP was 1.69 + 0.993. Most of the patients had drug therapy problem. Presence of heart failure (AOR: 8.001) had significant association. Number of co morbidity had significant association with number of DTPs while number of drugs didn't. As the number of co morbidity increases by one unit, there is 28.2% increase in number of DTP. © 2014 iGlobal Research and Publishing