Abstract
The study aims to evaluate the drug therapy in breast cancer patients in a tertiary care teaching hospital. A prospectiveobservational study was carried out for 6 months among breast cancer inpatients of either sex, with age ≥18 years with or without co-morbidities. Demographics of the patients, co-morbidities, chemotherapeutic drug regimens used, ADRs associated with chemotherapy and severity of pain were recorded. A total of 77 breast cancer cases were collected, among them 75 were females and 2 was male. Nine chemotherapeutic drug regimens (8 drug combinations+1 single drug regimen) were prescribed, out of which the most commonly used chemotherapy single drug regimen was Inj. Docetaxel (47.3%) and combinationregimen was Inj. Cyclophosphamide + Inj. Doxorubicin (30%). Most frequent adverse effects seen in patients receiving chemotherapy was alopecia (96.4%) followed by nausea (85.4%) and vomiting (76.4%). The adjuvant therapy included anti-emetics(5-HT3antagonist), corticosteroids, H2antagonists, antihistamines, andantipyretics.
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