DRUG-RELATED PROBLEMS IN HOSPITALIZED GERIATRIC PATIENTS WITH DIABETES MELLITUS

Debby Dystra Maharani,Yetti Hersunaryati,Nadia Farhanah Syafhan

doi:10.22159/ijap.2018.v10s1.30

Debby Dystra Maharani, Yetti Hersunaryati + Show 1 more

Open Access

https://doi.org/10.22159/ijap.2018.v10s1.30

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Abstract

Objective: This study aimed at analyzing drug-related problems (DRPs) in hospitalized geriatric patients with diabetes mellitus.Methods: We prospectively collected data of 26 hospitalized geriatric patients at the Gatot Soebroto Army Hospital (age, >60 year) who underwentinpatient treatment for at least 1 month between February and April 2015. Readable data were obtained from prescriptions, medical records, andindex card/nurses records. We obtained data on 299 drug treatments for 26 patients and identified 166 DRPs. These were analyzed based on thePharmaceutical Care Network Europe Version 6.2.Results: The percentage of treatment effectiveness (50.6%) and adverse drug reactions (49.4%) was predominantly due to an inappropriate drug–drug or drug–food combination, including the incidence of drug interactions (20.4%).

Highlights

Indonesia ranks 4th among the countries with the largest number of diabetes mellitus (DM) cases worldwide, after India, China, and US, based on information obtained from the World Health Organization in 2006
We identified the presence of drug-related problems (DRPs) by filling out a list of contents based on the Pharmaceutical Care Network Europe (PCNE) V6.2 referring to the literature with the main domains of therapeutic effectiveness and adverse drug reactions (ADRs)
DRPs in geriatric patients with DM Data were prospectively collected with the total sampling method

Summary

Introduction

Indonesia ranks 4th among the countries with the largest number of diabetes mellitus (DM) cases worldwide, after India, China, and US, based on information obtained from the World Health Organization in 2006. There are two therapeutic approaches for individuals with DM - with or without drugs. Treatment without drugs is based on specific dietary guidelines, known as nutritional therapy, and physical activity. If this approach does not lead to the therapeutic goal, drugs are introduced. Pharmacological steps can be in the form of insulin therapy, oral hypoglycemic drug therapy, or a combination of both [1,2,3]. Insulin is the treatment for patients with type 1 DM, whereas oral hypoglycemic drugs are intended to help in the treatment of patients with type II DM. The management of DM with drug therapy may lead to drug-related problems (DRPs) and an inability to achieve therapeutic goals.

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