Abstract
Medication related adverse events are an important cause of hospital admission or prolonged stay. To assess medication related adverse events in a hospital discharge database. Revision of the Chilean hospital discharge database from 2010 to 2017 searching for ICD- 10 diagnostic codes corresponding to medication related adverse events. The number of medication related adverse events was stable across the studied time lapse, but admission length increased. Between 34 and 111 people died every year due to medication related adverse events. Lactating babies, toddlers, adolescents and people over 80 years of age are at greater risk of experiencing these events. Medication related adverse events are more common than expected.
Highlights
Medication related adverse events are an important cause of hospital admission or prolonged stay
Material and Methods: Revision of the Chilean hospital discharge database from 2010 to 2017 searching for ICD- 10 diagnostic codes corresponding to medication related adverse events
The number of medication related adverse events was stable across the studied time lapse, but admission length increased
Summary
Medication related adverse events are an important cause of hospital admission or prolonged stay. Creemos que el número real de daño producido por medicamentos en Chile podría estar en algún punto intermedio entre las cifras calculadas con ambos sets de códigos. Este estudio tiene el objetivo de estimar la magnitud del daño producido por medicamentos en los egresos hospitalarios del período 20102017, mediante dos grupos de códigos CIE-10, que representan una visión conservadora de la estimación y una menos conservadora. Al cruzar los casos con daño según cada código y condición de egreso “fallecido”, obtenemos las muertes por uso de fármacos y abuso de drogas (Tabla 3). Cabe destacar que solo 8 muertes detectadas corresponden a códigos F1XX para ambos sets durante todo el período del estudio, lo que indica que se detectan más muertes por uso de medicamentos que por el abuso de drogas. La tasa de letalidad es calculada como porcentaje de personas dañadas que presentan condición de egreso fallecidas
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