Drug Profile and Therapeutic Adherence of African-Brazilians with Apparent Resistant Hypertension

Pedro Henrique Andrade Araújo Salvatore Barletta,Breno Lima De Almeida,Tayla Samanta Silva Dos Santos,Vitor Fernandes De Almeida,Roque Aras,Mateus Andrade Bomfim Machado,Yana Mendonça Nascimento,Thaise Almeida Silva,Júlia Lasserre Moreira,Cristiano Macedo

doi:10.36660/ijcs.20200117

Pedro Henrique Andrade Araújo Salvatore Barletta, Breno Lima De Almeida + Show 8 more

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https://doi.org/10.36660/ijcs.20200117

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Abstract

Background Resistant hypertension (RH) is manifested by the presence of blood pressure values resistant to antihypertensive therapy. RH is highly prevalent among black individuals, increasing cardiovascular risk in this population and requiring effective control of this comorbidity. Objectives To investigate the medication profile and therapeutic adherence in black people with apparent RH. Methods This is a cross-sectional study, with a convenience sample of individuals with apparent RH. Data were obtained from medical records. Therapeutic adherence was assessed using the [...]

Highlights

Systemic hypertension (SH) is an important risk factor for cardiovascular events, especially stroke, which justifies the relevance of its proper management
It was evidenced that two-thirds of the individuals did not have high therapeutic adherence and not all used the ideal regimen for the management of Resistant hypertension (RH), nor full doses
Most individuals were probably affected by pseudoresistance, which was initially diagnosed as apparent RH. (Int J Cardiovasc Sci. 2021; 34(3):300-306)

Summary

Introduction

Systemic hypertension (SH) is an important risk factor for cardiovascular events, especially stroke, which justifies the relevance of its proper management. Despite this high prevalence, pressure control is achieved in most cases with the appropriate choice of antihypertensive drugs.[6] still 9-18% of individuals with SH have blood pressure levels resistant to pharmacological treatment, which characterizes resistant hypertension (RH).[6,7,8]. Resistant hypertension (RH) is manifested by the presence of blood pressure values resistant to antihypertensive therapy. RH is highly prevalent among black individuals, increasing cardiovascular risk in this population and requiring effective control of this comorbidity

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