Drug Monitoring and Clinical Chemistry

Abstract

Sample preparation for the analysis of drugs in biological fluids (Yoshihiro Saito et al.). Chromatographic methods for the analysis of drugs in biological fluids (Hassan Y. Aboul-Enein et al). Capillary electrophoresis for the determination of drugs in biological fluids (Zakariya K. Shihabi). Immunoassays for the therapeutic drug monitoring and clinical toxicology (W. Clarke). Validation of bioanalytical methods (S. Berthier). Pharmacokinetic methods for the analysis, interpretation and management of TDM data, and for individualising drug dosage regimens optimally (R. Jelliffe et al.). Dose and therapy individualisation in cancer chemotherapy (G. Hempel). Rationale and utility of therapeutic drug monitoring for the optimisation of antibiotic therapy (C. Ong, D.P. Nicolau). Therapeutic drug monitoring of antiepileptic drugs (S.I. Johannessen). Therapeutic drug monitoring of antipsychotic and antidepressant drugs (P.B. Mitchell). Monitoring immunosuppressant drugs (D.W Holt, A. Johnston). Pharmacogenomics: methodologies for genotyping and phenotyping (P. Jannetto et al.). Applications of genotyping and phenotyping for clinically relevant polymorphisms of drug metabolizing enzymes and drug transporters A. Lazar et al.).