Abstract

Drugs can interfere with the biochemical assessment of nutritional status through analytical or biological effects (Roe 1981). Analytical effects include all interferences that result from chemical interactions in the test procedure (see Table 8.1). It is generally accepted that these effects are not caused by any in vivo nutritional changes caused by the drug. Conversely, biological interference involves a drug-nutrient interaction in vivo that affects nutritional status (see Table 8.2). Analytical effects involve a change in test values that is similar in all samples from patients who have received similar doses of the drug.

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